M11 B37- Sickle cell disease

Q. True about sickle cell disease are all except:

a. Single nucleotide change results in change of glutamine to valine.
b. Sticky patch is generated as a result of replacement of a non-polar residue with a polar residue.
c. HbS confers resistance against malaria in heterozygotes.
d. RFLP results from a single base change.



                                                                            Ans: b. Sticky patch is gen.....