M11 Pe115- Respiratory distress

Q: A 3.5 male infant born at term after an uncomplicated pregnancy and delivery develops respiratory distress shortly after birth and requires mechanical ventilation. The chest radiograph reveals a normal cardiothymic silhouette but a diffuse ground glass appearance to the lung fields. Surfactant replacement fails to improve gas exchange. Over the first week of life, the hypoxemia worsens. Results of routine culture and echocardiographic findings are negative. A term female sibling died at 1 month of age with respiratory distress. Which of the following is the most likely diagnosis:

(a) TAPVC
(b) Meconium aspiration
(c) Neonatal pulmonary alveolar proteinosis
(d) Disseminated herpes simplex infection.



                                                                                                   A: c. Neonatal....